Pharmacodynamics, Pharmacokinetics and ADME
• In vitro ADME
• Transporter research (Caco-2 cell test)
• Plasma protein binding rate test
• Metabolic enzyme related research (inhibition, induction)
• Metabolic stability (liver cells, microsomes, etc.)
• Metabolic phenotype (recombinant enzyme method)
• In vitro metabolite identification
• Drug-Drug interactions
• In vivo ADME
• Plasma concentration-time curve
• Bioavailability
• Material Balance
• In vivo metabolic pathway research
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